In active disobedience to God's command to "Be fruitful, multiply, and fill the earth," Ham's descendant, Nimrod, the so-called "mighty man," leads the people in centralizing the population, the culture, and the abandoning God's mission, to instead, build a mighty tower "up to the heavens." And the refusal to obey God, again, like in the Garden, has swift consequences. God takes away their ability to communicate - the most basic aspect of humanity.