Breathe Easy

In this episode, we have the pleasure of sitting down with Dr. Parth Rali to discuss two foundational articles on pulmonary embolism treatment. We will discuss the 2002 MAPPETT III trial and 2014 PEITHO trial. Both were published in the New England Journal of Medicine.

Show Notes

Show Notes

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Recommended Reading 
  1. Konstantinides S, Geibel A, Heusel G, et al. Heparin plus alteplase compared with heparin alone in patients with submassive pulmonary embolism. N Engl J Med 2002; 347:1143-50. 
  2. Meyer G, Vicaut E, Danays T, et al. PEITHO investigators. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med 2014; 370:1402-11.
  3. Supplement to: Meyer G, Vicaut E, Danays T, et al. Fibrinolysis for patients with intermediate-risk pulmonary embolism. N Engl J Med 2014;370:1402-11. DOI: 10.1056/NEJMoa1302097
  4. Rali P, Criner GJ. Submassive Pulmonary Embolism. Am J Respir Crit Care Med 2018; 198(5):588-98. 
  5. Chaudhury P, Gadre SK, Schneider E, et al. Impact of multidisciplinary pulmonary embolism response team availability on management and outcomes. Am J Cardiol 2019; 124:1465-69. 
  6. Konstantinides S, Vicaut E, Danays T, et al. Impact of Thrombolytic Therapy on the Long-Term Outcome of Intermediate-Risk Pulmonary Embolism. J Am Coll Cardiol. 2017 Mar, 69 (12) 1536–1544.

Creators and Guests

JM
Host
Jennifer D. Duke, MD
Mayo Clinic
Host
P.J. Gary, MD
SUNY Upstate Medical University
PM
Guest
Parth Rali, MD
Temple University

What is Breathe Easy?

Conversations in Pulmonary, Critical Care and Sleep Medicine by the American Thoracic Society