Lab Medicine Rounds

In this episode of “Lab Medicine Rounds,” Justin Kreuter, M.D., sits down with Shane Ferraro, M.H.S., PA(ASCP), an assistant supervisor of pathologists’ assistants in the Division of Anatomic Pathology at Mayo Clinic in Rochester, Minnesota, to talk about the important innovation of 3D scanning in pathology.

Timestamps:
0:00 Intro

00:54 Why is 3D scanning an important innovation in pathology?

02:51 Are there certain activities you can do with the audience that you weren’t able to do before? Are there certain insights you are hearing from the learners when you are doing that kind of approach?

03:40 What do you think is important for our audience to understand about 3D scanning?

06:12 What are some of the practicalities for implementing 3D scanning in a pathology practice?

08:23 Are there different teams that you are interacting with outside of pathology that is helping to make some bridges between pathology and other clinical departments?

09:22 In pathology, it sounds like it got started with forensic pathologists, and now it’s being brought out to the surgical practice?

10:12 How long does it take to scan some tissue? Is it relatively quick or like a day-long process?

11:40 Is this thought to replace surgical pathology photography in the next 5-10 years?

12:29 Where do you see this innovation going over these next 5-10 years?

14:46 Outro

What is Lab Medicine Rounds?

A Mayo Clinic podcast for laboratory professionals, physicians, and students, hosted by Justin Kreuter, M.D., assistant professor of laboratory medicine and pathology at Mayo Clinic, featuring educational topics and insightful takeaways to apply in your practice.

This is Lab Medicine
Rounds, a curated podcast

for physicians, laboratory
professionals, and students.

I'm your host, Justin Krueter,
the Bow Tie Bandit of Blood,

a Transfusion Medicine
pathologist at Mayo Clinic.

Today we are rounding with Shane Ferraro,

a Pathologists' Assistant,
Assistant Supervisor

in the Division of Anatomic Pathology

at Mayo Clinic in Rochester, Minnesota,

to talk about the important
innovation of 3D scanning.

Thanks for joining us today, Shane.

Yeah, my pleasure.

Thanks for having me.

Very exciting.

Yeah. So 3D scanning is
something that I think a lot

of us are starting to kind of hear about.

Some of us are probably
getting a chance to see

about this innovation.

I'm curious, from your perspective

why is 3D scanning an an
important innovation in pathology?

Yeah, it's a, it's a
very exciting question

and a very exciting topic.

So from all of my experiences

with our 3D scanning system so far

I think the most important
impact is on education.

And for instance, so

with our pathologist assistant team,

we're heavily invested in
resident and PA student education.

So the applications of this
technology really allow

for like a versatile and
kind of conducive approach

to how people in anatomic pathology learn.

So we're very visual learners,

we're very hands-on, and
that's an extension

from our experience in like cadaver labs.

And, you know,

as we were to the frozen section lab here,

surgical pathology labs in general.

So the the applications
of the technologies here,

can really be fostered in a way to,

create environments that
are more conducive to learning.

So for instance, with this
technology, we can create things

like QR codes, which you
can bring to a presentation

and you can have the audience kind of scan

that with your phone,
and then they could look

at a 3D model that you
created on their phone.

So they get a really interactive
experience with that.

In addition to that

we also have the ability to
create actual tangible 3D models

from the specimens that we have scanned.

So when we do that

we can actually have those models shared

in an environment that's, that's not a

an actual like pathology lab.

So you don't have to worry
about safety precautions.

You don't have to worry

about balancing clinical
care with resident education.

So you can really hone in
on some of those skills

and really foster a good
environment for them to learn

in. So, very exciting
from that angle for us.

Yeah, I mean, it sounds really
almost transformative, right?

I think you mentioned a couple
of things that you can do

that we haven't really
been able to do before.

You mentioned, so with a 3D scan

that we're able to really
take anatomic models

and we can kind of,

the audience can play
with them on their phone.

And I'm curious, like when
you talk about, you know

educational change that's happening

because you can get the audience do that

are there certain
activities that you can do

with the audience that you
weren't able to do before?

Are there certain insights
that you're hearing

from the learners when you're
doing that kind of approach?

It's hard to really know

because this is
something that we just received

and as I mentioned, like, so all

all of our PA educators
are, are really excited.

I've had several of them already asking

about the opportunities to
actually get their own specimens

and their QR codes to share.

So the enthusiasm is there.

I can't quite comment
on how it might transfer

into an audience kind of
engagement, but just the fact

that somebody could get
their phone, scan the QR code

and then just you can
hear all the audible ooh's

and ah's as they go through a specimen.

It sounds like a very exciting thing.

And I look forward

to having those opportunities with people.

So

Yeah. Absolutely.

So what do you think is important

for our audience to
understand about 3D scanning?

So two, two things come to mind.

You know, we talk

about 3D scanning as if
it's like some kind of

really like futuristic abstract technology

when in reality it's,
it's more simple than that.

So the machine is, you know,

it's this big cube and
we would put the specimen

inside this chamber
and it would have,

it's mounted on a rotating platform

and we could kind of choose
like what kind of, you know

mount it's on, it could be
a glass surface, it could be

like a pin mounted method,
or we can do like,

it's a resting kind
of mesh kind of screen.

So it's on this, this, this mount

and then it's in the chamber

and there's several cameras
kind of lined along the edge.

So the specimen will rotate

and the cameras are just
taking multiple photos

of it as it rotates.

So it's just a really
fancy kind of camera setup.

So those photos actually act as the

the data for the 3D model to be rendered.

And these models are
really like crisp and clean

and this is like, it's
very simple and very scalable.

So it's something

that I think will be much
more prevalent going forward.

The other

the other thing that I
think is really interesting

about this is, I talk about
the education side a lot

and that actually transfers
over towards patients too.

So for instance, here

with our PA service and
our pathology service,

we see a lot of heart
and lung transplants.

So we actually have a
service where patients

can request this upfront.

They can,

they can request to see
a scan of their specimen.

So the, the patient could come

in after they've had
their lungs, you know, removed.

They have a new set of lungs

they can come in with
their family and they could,

they can talk to the
actual pathologist who

reviewed the actual specimen,
the, the patient's lungs.

They took sections to
look at microscopically

and they could get a one-on-one
interactive session to

kind of go over the specimen

and kind of really see

the cycle of care.

And then they can also go
home with that specimen

so they can have a, a memento
and a reminder of the service

and the care that they
experience here at the clinic.

So there's some
really cool things, you know

that are happening in addition to like

just the education that
goes along with this.

So

You know, another thing that
comes up in my mind is, I

I mean, you're a pathologist
assistant, you know

are you taking this
home to show your family

members what kind of stuff you deal with?

I'm excited to,
I have to be careful.

I mean, I could tell my wife
about some of these things

but she doesn't wanna hear it as much.

So I gotta, I have to
make sure I pick the right

kind of specimen to bring
home that might not

hit those kinds
of buttons for some people.

Oh, I,

I understand that. That
kind of gets us into, you know

what are some of the practicalities

for implementing 3D scanning
and a pathology practice?

Right. You mentioned that
you're seeing this as really a

a very scalable technology.

Yes. So going back to kind of how

I mentioned how
it's, yeah, it is scalable

and it's a really
simplified kind of setup.

So right now we're

launching this system
in our frozen section lab

which is a rapid
intraoperative diagnosis lab.

So it's a very clinical heavy setting.

We, provide intraoperative
results to surgeons

so that they can know how to
advance with their procedures.

So balancing that kind of aspect

of our work with getting some

of these educational
requests, is a hurdle.

You know, so as we kind
of learn how to, how to

balance our work and really
accommodate these requests

because for the most part

this is primarily an
educational kind of setup.

There are, you know, ideas
to kind of expand this

into a more clinical kind of
aspect, but right now it's

it's really finding that, that
that sweet spot to get the

get our pathologist and the
surgeons the answers they need

and really make sure that we
can streamline our processes.

And, you know, that, that
might be something as simple as,

as I mentioned earlier

there's different mounting techniques.

So for instance

if you have something that
might be more soft, like a

like a fatty kind of tumor
that's really squishy

and just kind of sits, you're

you're not going to be able
to put that on like a

a pin mounted method.

You're going to have to put
it on the glass surface.

If you have something like a
bone, which might look weird

or it might stand at an awkward angle

using that glass might not work.

So kind of making sure
that we can rapidly kind

of put together the mounting
technique, get a good scan,

get the surgeon what they need,

get the consultant what they need,

and make sure all kind
of parties are involved,

is probably the biggest
hurdle in, in my mind.

And are there different teams
that you are interacting with

like outside of pathology
that is helping to kind

of bridge to make some bridges

between pathology and
other clinical departments?

So, right, so the system that we use

the actual scanning system
is called Med Creator.

We're supported by a thing,
which is the company named

they're based out of Chicago

and they have other
departments here that they

they collaborate with.

So we haven't really worked too much

outside of our department.

We work closely with the
autopsy lab who really

pioneered a lot of this, these techniques

and kind of helping support
this growth of the technology.

So we work closely with them

but otherwise outside of
like surgical pathology and

you know, anatomic pathology

we haven't worked with too
many other departments.

I'm excited for those opportunities.

I know in the past

as this kind of technology
was more experimental

there were different
opportunities we had with

I think it was radiology
who did want to like

coordinate with certain specimens.

So we did have those
opportunities in the past

which was a lot of fun.

I had a lot of fun with that.

So

Yeah. And you mentioned,
you know, in pathology

it sounds like it kind of
got its route started

with forensic pathologists

and then you're saying now
it's kind of being brought

out to the surgical practice?

Yeah, so our, our autopsy
lab, it, it functions as a

a medical or an in-house
autopsy lab

in addition to the, the
forensics pathology service.

So those, it was more
or less those medical,

those kinds of autopsies, those
educationally approved

for cases where we were kind of expanding

on some of this technology.

Their interfaces
are a little bit more complex

and as I mentioned before

thing has been able to really condense

and simplify all the
applications and, you know

for instance, the software
that controls how the

the mounting station
kind of rotates, stops

the cameras engage, all

of all that stuff was kind
of worked together in autopsy

and they really like
consolidated those applications.

Hmm. And, and how long does
it take to scan some tissue?

Is this something
that is relatively quick

or is this like a day long process?

It's actually, yeah, I
didn't even think about how

I'm commenting on how interesting this is.

So it's really simple.

It's really quick actually.

So we would just need
to go into the software

the software that they've
made, this kiosk application

we would just need to basically adjust the

the camera settings and you could adjust

like the model quality,
but it's not necessary.

So you would just put in
your settings, name your file

hit the button, and it
takes about five minutes

for these pictures to be taken.

So once the pictures are taken,
you can open up the chamber

and retrieve your specimen.

And then the, the actual
rendering of the model

will take 20 minutes.

So you can, you can have a
really quick turnaround, but

in the grand scheme of things,
those five minutes are really

important for a patient who's
on the operating table.

So you have to still
balance making, you know

making sure you're
getting those results back

to your surgeon and the consultant.

But it, it is very quick,
relatively speaking, so

Oh wow.

It's interesting.

Yeah. You know, so quick to scan.

And then also it sounds like
if everybody's able to get

on their cell phone and
manipulate it, it's not like

the old kinda lag time of, you know

you have to make sure
you're on good internet.

Correct. And yeah, so we can look

at the model real time on the system.

Once it's, we can

we can look at it on our
screen as, as it's rendered

and we can kind of look at
it and say, you know what

maybe maybe we should try
to get a better angle or, no

this is great.

You know, we can

we can know real time if
what we have is good.

Is the thought is this going to replace?

I know there's always been
kind of surgical photography

or surgical pathology photography.

Is, is this thought to replace this

in the next five, 10 years?

In my mind, no.

I don't.

I think that there's too much
value in photography itself.

3D models have their place
and you know, they really

they really can fit into the picture.

Sorry for the pun,

but I don't think that
photography is gonna go away.

There's just you, there's too
much pop, there's too much pop

to photographs that you
kind of lose in a 3D model.

And I, I enjoy taking
photos of our specimens

and I take a lot of pride in it

so I don't want to see that
go away anytime soon.

Yeah, no, I, I really appreciate
your kind of nuance too.

You know, it's not

like the panacea that's
gonna replace everything.

There's a time and a place
these certain things.

So I guess that kind of brings me

to my final question of
where do you see, you know

this innovation going over
these next five, 10 years?

Yeah, it's, it's fun.

It's really fun to think about that.

And it's, I get a lot

of like insights from
our PA team and

they have some plans,
they have some concepts.

One of the really interesting things is

as I mentioned before, you know, we could

you can print 3D models, but what you

you can also do is you could change colors

of certain anatomic sites or
structures on these models.

So we can create like unique

really unique models to
show the relationships

of adjacent structures.

And that's, that's a significant

it's a really important skill to have

in anatomic pathology and gross anatomy.

So we can do that.

And I think another kind
of step I would like to see

which really kind of
takes that to like the enth

degree would potentially
be the applications

for augmented or virtual reality options.

So what I'm thinking is, like,

you could take a specimen,

so you could take a kidney specimen,

so you could take an
overall scan of the specimen,

and then you could do
like a step-by-step scan

as you would grossly examine the specimen

and grossly examine like
if there's a tumor present,

how it relates to adjacent structures.

And you can provide a
step-by-step gross examination

of that for a learner.

And they could have, they could pop

on a VR set and kind of go
through the whole, you know

the whole steps and the

the maneuvers of grossing in
a, like a surgical specimen.

Or they can have some kind of a

some other kind of like
goggle system that provides

like an augmented reality
system so that they can see

out of their periphery of
the side of their vision

like the actual step-by-step process of it

while they're going through
an actual surgical specimen.

It's, it's a lot of fun to
kind of think of these things.

I have no idea if they're 100% applicable

but it's a lot of fun to
kind of get these ideas

and see if they're, they're possible.

Yeah, I'm really excited by that.

I think something that
young learners in the field

of pathology struggle
with is sometimes looking

at something that's 2D and
having to kind of construct this

as a 3D and it, it sounds
like there's some wonderful

that may not always be
the case going forward.

Yeah, it's, I get, I'm excited.

I think this provides
a unique opportunity

for people to learn because maybe

maybe they're really
intimidated by an actual

like specimen when they first see it

so can provide a more
controlled environment

for them to get that hands-on experience

and the visual kind of
correlation between what they read

in the book, versus what it actually is.

So, very cool opportunities.

Brilliant. Hey, we've been
rounding with Shane Ferraro.

Thank you for taking the time to talk

about 3D scanning with us today.

Yeah, my pleasure.

Thanks so much.

And if you'd like to
hear more on this topic,

Shane will be presenting

at the 2023 Pathologist's
Assistant Symposium in June.

Please visit
mayocliniclabs.com/2023PAsymposium

for more information.
To all of our listeners,

thank you for joining us today.

We invite you to share your thoughts

and suggestions via email.

Please direct any suggestions

to mcleducation@mayo.edu
and reference this podcast.

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