Pulse field ablation (PFA) has been hailed as the next frontier in atrial fibrillation therapy—nonthermal, ultra-selective, and lightning fast. But as new data emerges, important questions are rising about its systemic effects, cerebral safety, and vascular complications.
In this episode of EP Edge, Dr. Niraj Sharma unpacks the latest findings from the NEMESIS-PFA registry, explores silent cerebral lesion data, reviews a rare case of catastrophic coronary spasm, and introduces how AI—through models like DeePRISM—is changing how we think about ablation strategy.
Whether you’re in the lab, in clinic, or leading research, this episode offers a critical look at where the field is heading next.
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For feedback, collaborations, or questions, email Dr. Niraj Sharma at epedgecast@gmail.com
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What is EP Edge?
EP-EDGE brings you the latest in cardiac electrophysiology — from breakthrough research and clinical insights to future-shaping innovations. Hosted by Dr. Niraj Sharma, an electrophysiologist with over 15 years of experience, each episode delivers clear, evidence-based updates designed to inform, inspire, and elevate your practice.